Stronger protective skin barrier
- Deep hydration and nourishment
- Refined skin texture and quality
Niacinamide
supports the barrier, refines texture
- Ceramides
- replenish the lipid barrier
- Shea butter
- nourishes and softens skin
How to use
- Apply a small amount to cleansed skin
- Massage in gently until fully absorbed
- Use morning and evening
Hylanses Md Ha Advance Nourishing Cream Mediderma
Nourishing cream with niacinamide and ceramides
Deeply hydrating and nourishing face cream for mature skin and skin that requires intense hydration. Niacinamide, ceramides, shea butter, and olive oil strengthen the skin barrier, while high and low molecular weight hyaluronic acid hydrates on the surface and in depth.
- Strengthens the skin's protective barrier
- Deeply moisturizes and nourishes
- Improves skin texture and quality
- Regulates moisture levels
- Supports anti-aging action
- For day and night use
Deep hydration for mature skin
HA Advance Nourishing is a deeply hydrating and nourishing cream enriched with active ingredients that help strengthen the skin barrier, improving its texture and quality. Designed for mature skin that requires intense hydration.
What works in the formula
Barrier, hydration, and texture
Niacinamide, ceramides, shea butter, and olive oil work in synergy — improving the skin's barrier function, regulating hydration, and enhancing its texture. Hyaluronic acid with two molecular weights works at different levels, providing hydration on the surface and deep within.
Daily ritual
- 1Apply a small amount of the product to previously cleansed skin.
- 2Gently massage until fully absorbed.
- 3Use both morning and evening.
Indications
- Mature skin
- Skin requiring intense hydration
- Weakened barrier and uneven skin texture

„“Mediderma is the dermatological brand of Dr. Gabriel Serrano — liposomal formulas with high concentrations of active substances, which I recommend to clients expecting real results, also for sensitive skin and after treatments.””
I'll gladly advise whether Hylanses Md Ha Advance Nourishing Cream will work for your needs — answer a few questions in the skincare finder and we'll immediately match the care to your skin and the order of use.
Recommended by our cosmetologist · loved by clients
Not sure which Mediderma preparation to choose for your complexion? Write to us — we will help you match skincare tailored to your needs.
Write to us →The full line Mediderma
Complete dermatological care by dr. Serrano — cleansing, treatment, protection. Build your set.



















































